Item# 115-30: Murine anti-38kD TB Antigen Monoclonal Antibody
Antibody Class: IgG Clone 8D2
Concentration: See vial
Physical State: Frozen Liquid
Stability: At least 24 months at -75°C
Applications: ELISA, Western ELISA, Immunoprecipitation
Description: High affinity murine anti-38kD TB Antigen mAb.
Specificity: Binds to 38kD TB antigen as determined by Elisa/Western Elisa. This mAb shows reactivity with native 38kD TB antigen – M. tuberculosis cell lysates.
Biological Activity: Not determined.
Application and Instructions for use:
Recommended dilutions for use are approximate values. A dose dependent response assay should be performed to determine the optimal concentration for use in specific applications. ELISA may be performed at 1ug/ml of mAb depending on the amount of immobilized antigen in the assays. Western ELISA requires 1-5µg of mAb/ml.
Definition of murine antibodies:
Antibodies, also called immunoglobulins, make up the main part of the specific endogenous defence. They are made by the immune system in response to substances which are foreign to the organism (antigens = antibody generating). Donor organisms like mice and rats are being used for the production of specific antibodies. Those are referred to as murine (belonging to the family muridea = rodents) antibodies.